Fiber Tracking

Before practicum on Friday, please complete following:

During practicum on Friday:

1.Introduction to tractography

image

Local fiber orientations derived from dMRI

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source: source: http://jmahaffy.sdsu.edu/courses/f00/math122/lectures/num_method_diff_equations/nummethod_diffeq.html

2.Limitations

source: Yeh, Fang-Cheng, et al. “Tractography methods and findings in brain tumors and traumatic brain injury.” NeuroImage 245 (2021): 118651.

source: https://www.nature.com/articles/s41467-017-01285-x/figures/7

source: Wu, Ye, et al. “Mitigating gyral bias in cortical tractography via asymmetric fiber orientation distributions.” Medical image analysis 59 (2020): 101543.

3.Region types used in fiber tracking

4.Fiber tracking protocols


Assignment:

1. Combine automatic fiber tracking and region-based fiber tracking

  1. Use [AutoTract] to map left corticospinal tracts on 100206.src.gz.gqi.1.7.fib.gz

  2. Identify false results and use ROI-based fiber tracking to improve the results.

  3. [Optional] write a script to map CST in multiple FIB files(Download 3~5 FIB files)

    • rename the regions files to include “mni” in the file name, and DSI Studio will load it as MNI regions
    • examples

2. Mapping difficult pathways using region-based fiber tracking

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  1. Download HCP1065 1-mm FIB file

  2. Use region-based fiber tracking, map the orbital connections in nuclei 5.

  3. Use region-based fiber tracking, map the temporal connections in nuclei 5.

  4. Use region-based fiber tracking, map the occipital connections in nuclei 5.